The applicability domain of the QSAR will be provided to you the moment you request a quote. If KREATiS is not confident that your molecule is covered you will be told before signing a quote. If you wish to verify the applicability domain further to receiving the report, refer to the QSAR Model report where a complete section is dedicated to identify the chemical groups to which the model can be reliably applied. There are several well-known approaches to define the Applicability Domain of the QSAR models, thus depending upon the algorithm implemented the strategy used to address the reliable chemical space may differ. If your substance of interest satisfies all the conditions specified for the model’s applicability, you can rest assured that the endpoint value has been reliably predicted.
A tutorial will be shortly made available on this website to provide an introduction to the existing Applicability Domain approaches.